5條路線長短不同，分別根據 5 個奧比斯眼科飛機醫院服務國家— 越南、蒙古、印度、埃塞俄比亞及秘魯—與香港的飛行距離為藍本而設計。當中越南線、蒙古線及埃塞俄比亞線分別由崇光百貨、捷成集團、Johnson & Johnson三間公司贊助，參加者每跑1公里，公司就會捐出$10，支持奧比斯的救盲工作。
Five routes to select: Taking reference from the flight distances from the five countries the Flying Eye Hospital currently serves - Vietnam, Mongolia, India, Ethiopia and Peru - and Hong Kong, five different routes with varied lengths are set accordingly. Vietnam route, Mongolia route and Ethiopia route are sponsored by SOGO, Jebsen Group, and Johnson & Johnson respectively. They will donate HK$10 to Orbis for every km the participants ran.
Participants could participant as an individual and choose the following routes according to their interests and strength.
Participants could join as a team (2-8 members per team) and choose the routes according to their interests and strength.
Participants could join as a team (6-15 members per team) and choose the routes according to their interests and strength.